Change in Long-Spacing Collagen in Descemet's Membrane of Diabetic Goto-Kakizaki Rats and Its Suppression by Antidiabetic Agents

<table>Immunofluorescence localization
of type VIII collagen (red color) in Descemet’s membrane of the cornea from
62-week-old rats (a), (b) and Nomarsky microscopic images of the same optical
fields (c), (d). (a), (c) Wistar rat. (b), (d) GK rat. Green color (SYBR-Green I) indicates the nuclei
of endothelial cells. Dm: Descemet’s membrane; En: endothelial cell; S: stroma.
Scale bar: 10 <i>μ</i>m.</table>

Journal of Diabetes Research

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Figure 4

Figure 4: Change in Long-Spacing Collagen in Descemet's Membrane of Diabetic Goto-Kakizaki Rats and Its Suppression by Antidiabetic Agents 