Change in Long-Spacing Collagen in Descemet's Membrane of Diabetic Goto-Kakizaki Rats and Its Suppression by Antidiabetic Agents

<table>Inhibition by antidiabetic
agents of the formation of long-spacing collagen in 15-week-old GK rats. The
rats were administered methylcellulose alone (GK-Control), nateglinide
(GK-Nateglinide) or glibenclamide (GK-Glibenclamide) for 15 weeks, which agents
were suspended in methylcellulose. The number of long-spacing collagen fibrils
in the Descemet’s membrane was examined by electron microscopy. Data are
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</svg>.</table>

Journal of Diabetes Research

fig8

Figure 8

Figure 8: Change in Long-Spacing Collagen in Descemet's Membrane of Diabetic Goto-Kakizaki Rats and Its Suppression by Antidiabetic Agents 