Research Article
Decreased ADP-Ribosyl Cyclase Activity in Peripheral Blood Mononuclear Cells from Diabetic Patients with Nephropathy
Table 1
Baseline characteristics of subjects. Results are expressed as mean ± S.D.
| | Type
1 diabetes | Type 2 diabetes | Nondiabetic control |
| | Number of subjects | 10 | 50 | 15 | | Gender (male/female) | 5/5 | 26/24
| 6/9 | | Age (years)
| | | | | BMI (kg/m2) | | | | | Duration of diabetes (years) | | | — | | Fasting plasma glucose (mg/dl)
| 244 ± 130 | 164 ± 54 | 81 ± 12 | | HbA1c (%) | | | | | Medication for diabetes | | | | | Diet alone | — | 4 | — | | Oral hypoglycemic agents | — | 30 | — | | Insulin | 10 | 16 | — | | Diabetic complications | | | | | Nephropathy | 3 | 20 | | | Retinopathy | 4 | 22 | | | Neuropathy | 4 | 25 | | | Macroangiopathy | 0 | 18 | | | ADP-ribosyl cyclase activity (nmol/min/mg protein) | | | |
|
|
