Clinical Study
A Variation in the Cerebroside Sulfotransferase Gene Is Linked to Exercise-Modified Insulin Resistance and to Type 2 Diabetes
Table 4
Biomedical data from patients and controls displayed according to genotype at SNPs rs2267161. The serum sulfatide and insulin levels are in log units.
| | | Genotype C/C | Genotype C/T | Genotype T/T | | | Controls | Type 2 | Controls | Type 2 | Controls | Type 2 |
| Male | n | 66 | — | 60 | — | 52 | — | 67 | — | 18 | — | 12 | — | | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | Age | 58.5 | 10.4 | 63.9 | 7.9 | 57.7 | 9.6 | 65.8 | 6.8 | 56.2 | 10.2 | 66.9 | 6.1 | BMI | 26.3 | 2.8 | 28.3 | 4.1 | 26.6 | 3.1 | 28 | 4.3 | 26.1 | 2.2 | 28 | 5.7 | Sulfatid | 2.2 | 0.7 | 1.9 | 0.8 | 2.2 | 0.8 | 1.9 | 0.8 | 2.0 | 0.8 | 2.0 | 0.8 | Serum insulin | 0.7 | 0.3 | 0.9 | 0.4 | 0.7 | 0.4 | 1.0 | 0.6 | 0.6 | 0.4 | 1.0 | 0.2 | Fasting blood glucose (mmol/L) | 4.6 | 0.5 | 8.4 | 2.3 | 4.7 | 0.5 | 8.4 | 2.6 | 4.7 | 0.4 | 8.9 | 2.2 |
| Female | n | 71 | — | 47 | — | 68 | — | 65 | — | 16 | — | 14 | — | | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | Age | 58.9 | 9.7 | 65.3 | 8.1 | 57.7 | 10 | 64.1 | 8.7 | 61.1 | 10.9 | 68.3 | 5.4 | BMI | 27 | 5.6 | 29.2 | 5.4 | 26.5 | 4.5 | 29.9 | 4.7 | 26.3 | 4.7 | 31 | 4.7 | Sulfatid | 2.3 | 0.7 | 2.2 | 0.8 | 2.3 | 0.7 | 1.9 | 0.8 | 2.1 | 0.7 | 2 | 0.8 | Serum insulin | 0.6 | 0.5 | 1.0 | 0.3 | 0.7 | 0.3 | 1.1 | 0.4 | 0.8 | 0.4 | 0.9 | 0.3 | Fasting blood glucose (mmol/L) | 4.7 | 0.4 | 7.9 | 2.0 | 4.7 | 0.5 | 8.1 | 2.7 | 4.8 | 0.5 | 9.9 | 4.0 |
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