Research Article

The Metal Chelators, Trientine and Citrate, Inhibit the Development of Cardiac Pathology in the Zucker Diabetic Rat

Figure 1

Representative left ventricle pressure/volume loops from lean control, untreated ZDF, ZDF + trientine, ZDF + Citric Acid animals. Beat by beat analysis of changes in LV hemodynamic parameters plotted along pressure (y-axis) and volume (x-axis) indicates a shift to the right in the ZDF animals suggesting LV dilatation, which is corrected by both trientine and citric acid.
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