Comparison of Measurements of Autoantibodies to Glutamic Acid Decarboxylase and Islet Antigen-2 in Whole Blood Eluates from Dried Blood Spots Using the RSR-Enzyme Linked Immunosorbent Assay Kits and In-House Radioimmunoassays

Table 1

Estimation of positivity for GADA and IA-2A. Number of positive and negative patients (80 children newly diagnosed with type 1 diabetes; median age 10; range 2–18 yrs) and controls (120 healthy women; median 32; range 19–44 yrs) from Sweden.

Assay	Positive	Negative
	Patients ( 𝑛=80)
RSR-ELISA-GADA	37 (46%)	43 (54%)
In-house RIA-GADA	45 (56%)	35 (44%)
	Controls ( 𝑛=120)
RSR-ELISA-GADA	0 (0%)	120 (100%)
In-house RIA-GADA	NA	NA
	Patients ( 𝑛=80)
RSR-ELISA-IA-2A	47 (59%)	33 (41%)
In-house RIA-IA-2A	53 (66%)	27 (34%)
	Controls ( 𝑛=120)
RSR-ELISA-IA-2A	37 (31%)	83 (69%)
In-house RIA-IA-2A	NA	NA