Journal of Diabetes Research / 2010 / Article / Fig 3

Research Article

The Role of Rho Kinase in Sex-Dependent Vascular Dysfunction in Type 1 Diabetes

Figure 3

Effects of rho kinase inhibitors Y27632 (1  M (a) and (b)) and H1152 (1  M (c) and (d)) on contractions to serotonin in aorta from nondiabetic (left panels) and diabetic male mice (right panels). Inhibition of rho kinase with either Y27632 or H1152 decreased contractions of aorta from both nondiabetic and diabetic mice to serotonin (nondiabetics per group, diabetics per group, * compared to paired untreated).