C-Reactive Protein and Gamma-Glutamyltransferase Concentrations in Relation to the Prevalence of Type 2 Diabetes Diagnosed by Glucose or HbA1c Criteria in Chinese Adults in Qingdao, China
Table 3
Odds ratio (95% CI) for newly diagnosed diabetes corresponding to a one-standard deviation increase in continuous variables stratified by waist circumference categories. Only the variables entered into the final logistic regression model are presented.
Standard deviation
FPG 7.0 mmol/L and/or 2hPG 11.1 mmol/L OR (95% CI)
HbA1c 6.5% OR (95% CI)
HbA1c 5.6%* OR (95% CI)
Men
Waist circumference 90 (cm) ( )
Age (year)
10.41
1.46 (1.12,1.89)
—
—
Positive family history of diabetes
—
3.04 (1.60,5.77)
—
—
Gamma-glutamyltransferase (U/L)
0.72
1.59 (1.29,1.96)
—
—
Systolic blood pressure (mmHg)
19.25
1.38 (1.08,1.76)
—
1.30 (1.10,1.53)
Total cholesterol (mmol/L)
1.03
—
1.32(1.04,1.66)
—
School years 9 (9)
—
—
0.59(0.34,0.98)
—
Waist circumference 90 (cm) ( )
Age (year)
10.41
1.62 (1.21,2.19)
—
—
Positive family history of diabetes
—
2.42 (1.28,4.58)
—
—
Low-density lipoprotein cholesterol (mmol/L)
0.97
1.61 (1.23,2.10)
—
1.61 (1.28,2.02)
Triglyceride (mmol/L)
1.10
1.64 (1.26,2.14)
—
—
School years 9 (9)
—
—
0.46 (0.25,0.85)
—
Body mass index (kg/m2)
2.52
—
1.50 (1.05,2.15)
1.27 (1.01,1.60)
Smoking
—
—
2.29 (1.24,4.22)
—
All ( )
Age (year)
10.41
1.65 (1.37,1.99)
—
—
Positive family history of diabetes
—
2.35 (1.50,3.66)
—
—
Gamma-glutamyltransferase (U/L)
0.72
1.42 (1.18,1.72)
—
—
Low-density lipoprotein cholesterol (mmol/L)
0.97
1.26 (1.06,1.49)
—
1.32 (1.17,1.49)
Triglyceride (mmol/L)
1.10
1.30 (1.11,1.52)
—
—
School years 9 (9)
—
—
0.50 (0.34,0.74)
—
Total cholesterol (mmol/L)
1.03
—
1.24 (1.04,1.47)
—
Women
Waist circumference 80 (cm) ( )
Age (year)
9.74
1.75 (1.26, 2.44)
—
—
Positive family history of diabetes
—
2.42 (1.12,5.21)
—
—
Gamma-glutamyltransferase (U/L)
0.54
1.83 (1.32,2.54)
—
—
School years 9 (versus 9)
—
—
0.31 (0.15,0.64)
—
Systolic blood pressure (mmHg)
22.42
—
—
1.34 (1.09,1.64)
Waist circumference 80 (cm) ( )
Age (year)
9.74
1.47 (1.19,1.82)
—
1.19 (1.04,1.36)
C-reactive protein
1.02
1.30 (1.11,1.51)
—
—
Gamma-glutamyltransferase (U/L)
0.54
1.56 (1.27,1.91)
—
—
Systolic blood pressure (mmHg)
22.42
1.22 (1.02,1.48)
—
—
Triglyceride (mmol/L)
0.80
1.57 (1.30,1.89)
—
—
School years 9 (versus 9)
—
—
0.44 (0.26,0.75)
—
All ( )
Age (year)
9.74
1.44 (1.19,1.73)
—
1.15 (1.02,1.28)
Positive family history of diabetes
—
1.66 (1.09,2.51)
—
—
Gamma-glutamyltransferase (U/L)
0.54
1.57 (1.31,1.87)
—
—
C-reactive protein (mg/dl)
1.02
1.21 (1.00,1.45)
—
—
Low-density lipoprotein cholesterol (mmol/L)
0.92
1.22 (1.04,1.43)
—
1.16 (1.04,1.29)
Triglyceride (mmol/L)
0.80
1.48 (1.26,1.74)
—
—
Systolic blood pressure (mmHg)
22.42
1.26 (1.06,1.49)
—
1.30 (1.10,1.53)
School years 9 (9)
—
—
0.36 (0.23,0.55)
—
Age, body mass index, gamma-glutamyltransferase, low-density lipoprotein cholesterol, triglyceride, total cholesterol, C-reactive protein, systolic blood pressure, family history of diabetes, school years, smoking, and alcohol-drinking are fitted in the models.C-reactive protein and gamma-glutamyltransferase were logarithmic transformed. *Optimal cutoff value for diagnosis of diabetes in this study population [16].
