Journal of Diabetes Research / 2010 / Article / Tab 2

Research Article

Fenofibrate Treatment Enhances Antioxidant Status and Attenuates Endothelial Dysfunction in Streptozotocin-Induced Diabetic Rats

Table 2

Emax and D2 values for control and diabetic rats.


Phenylephrine E(+)
Phenylephrine E(−)
Sodium nitroprusside

Data are expressed as mean ± SEM, .
is defined as the ratio of phenylephrine precontraction to maximum relaxation of acetylcholine, L-arginine, sodium nitroprusside, and calcium inonophore A23187.
is defined as −log EC50 concentration of drugs.
C: control; DM: diabetes mellitus; FF: fenofibrate; E(+): endothelium-intact aorta; E(−): endothelium-denuded aorta.
* versus C, # versus DM.