Development of a Nongenetic Mouse Model of Type 2 Diabetes

Figure 4

Body composition after STZ: (a) Fat tissue percentage, (b) lean tissue percentage, and (c) fluid percentage of body composition during the final week of trial. Male, retired breeder (6 mo.) C57BL/6 mice were used for this study. Values represent mean ± SEM (𝑁=5–8). *𝑃<0.05 versus respective control, ^#𝑃<0.05 versus respective LFD group, ^‡𝑃=0.06 versus respective LFD group, ^†𝑃=0.07 versus respective control.

(a) Fat tissue percentage, 4-wk after STZ

(b) Lean tissue percentage, 4-wk after STZ

(c) Body fluid percentage, 4-wk after STZ