Exercise Increases Insulin Content and Basal Secretion in Pancreatic Islets in Type 1 Diabetic Mice
Figure 6
Insulin secretion per islet. (a) Insulin secreted from isolated islets in low (3 mM) or high (16.6 mM) glucose was collected for 30 minutes. Under low glucose conditions, exercise improved the insulin secretion per islet significantly (#). Under high glucose, there was no effect of exercise. * control versus both diabetic groups. (b) When the insulin release was normalized for the total insulin content, exercise increased the percent of insulin released in basal conditions (#). With high glucose exposure, exercise induced a change in the insulin secretion, although it did not reach statistical significance.
