High Glucose Increases Metallothionein Expression in Renal Proximal Tubular Epithelial Cells

Table 1

Metabolic data at 1, 2, and 8 weeks after inducing diabetes.

		1 week	2 week	8 week
Body weight (g)
Control		204 ± 6.3	241 ± 10.4	380 ± 13.3
Diabetic		198 ± 4.7	225 ± 11.5	248 ± 16.6*
Kidney weight (mg/g BW)
Control		5.8 ± 0.4	5.6 ± 0.8	4.5 ± 0.7
Diabetic		5.9 ± 0.6	6.1 ± 1.0	6.7 ± 0.9*
UAE (μg/day)
Control		110 ± 7.3	121 ± 8.1	137 ± 14.7
Diabetic		116 ± 5.7	125 ± 9.4	458 ± 24.5*
HbA1c (%)
Control		3.7 ± 0.4	3.8 ± 0.6	3.8 ± 0.5
Diabetic		3.8 ± 0.3	4.3 ± 0.7	7.8 ± 0.9*

Data are means ± SEM; *𝑃<0.05 versus the control group. BW: body weight; UAE: urinary albumin excretion; HbA1c: hemoglobin A1c.