Neurovascular Interaction and the Pathophysiology of Diabetic Retinopathy
Figure 5
Nitrotyrosine expression in diabetic rat retina. Eyes were treated with saline (b) or with 5-methyl-I4AA (treatment). Nitrotyrosine expression was revealed by immunostaining with a polyclonal antibody (Chemicon) on cryosections of the retina. Arrows point to retinal blood vessels in both retinas. Arrowheads show staining of retinal ganglion cells in the diabetic retina but not in the treated retina. PR: photoreceptor layer, ONL: outer nuclear layer, OPL: outer plexiform layer, INL: inner nuclear layer, IPL: inner plexiform layer, and GCL: ganglion cell layer. Scale bar: 50 μm.
