Phenotypic Changes in Diabetic Neuropathy Induced by a High-Fat Diet in Diabetic C57Bl/6 Mice
Figure 3
Sensorimotor Behavior. (a) Mechanical sensitivity was assessed using 12 repeated applications of a 1.4 g von Frey monofilament ( mice per group). (b) Thermal sensitivity. Mice were placed on a Hargreaves apparatus, and a 4.0 V radiant heat source was applied to the hind paw footpad. The time elapsed before the animal withdrew the paw was recorded as withdrawal latency ( mice per group). (c) Sensorimotor ability was assessed by quantifying mean hind paw footslips as mice traversed a narrow wooden beam ( mice/group). Data are from 8 weeks after STZ and presented as means ±SEM. * and **.
