Research Article

A Novel EPO Receptor Agonist Improves Glucose Tolerance via Glucose Uptake in Skeletal Muscle in a Mouse Model of Diabetes

Figure 3

Dose response of CNTO 530 at day 14. PBS (■) or CNTO 530 was dosed IV at increasing concentrations (0.01□, 0.03♦, 0.1○, 0.3▲) in DIO mice ( ). (a) Fourteen days after dosing, an IPGTT was performed. (b) The AUC from part A was plotted for each dose of CNTO 530. The results are presented as mean ± SEM. **indicates a P value <  .01. ***indicates a P value <  .005.
910159.fig.003a
(a)
910159.fig.003b
(b)