Decreased Skin-Mediated Detoxification Contributes to Oxidative Stress and Insulin Resistance

<table>Plasma concentrations of nicotinamide and <svg height="15.975" id="M13" style="vertical-align:-0.1092pt" version="1.1" viewbox="0 0 21.3125 15.975" width="21.3125" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>-methylnicotinamide in different rat groups. Sham: sham-operated group; Sham + NM: sham-nicotinamide group; Burn: burn group; Burn + NM: burn-nicotinamide group. *<svg height="11.375" id="M14" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g><g transform="matrix(.017,0,0,-.017,50.481,11.113)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g>
</svg>. Bar graph indicates mean ± SEM.</table>

Journal of Diabetes Research

fig2

Figure 2

Figure 2: Decreased Skin-Mediated Detoxification Contributes to Oxidative Stress and Insulin Resistance 