Inhibition of Aldose Reductase by Gentiana lutea Extracts
Figure 3
Stereoview of ALR2 docked with amarogentin. (a) Amarogentin docked into the active site of ALR2 and extended towards hydrophobic pocket.(b) Amarogentin docked into active site of ALR2 and depicts its hydrogen bond interaction with residues Trp-20, His-110, and Leu-300 (dotted line) and hydrophobic interactions with Trp-219 (green dotted line).
