An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice
Figure 1
Morphometric analyses of the glomeruli of Akita mice. (a) Eight-week-old Akita mice and control mice received telmisartan (5 mg·kg−1·day−1, in their drinking water) or no treatment, respectively, for 15 weeks ( in each group). After 15 weeks, the mice were sacrificed, the kidneys were harvested, and periodic acid-Schiff staining was performed. (b) Quantification of sclerosis per glomerular area was performed with the ImageJ software. **, n.s.: not significant.
