Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients
Table 1
Clinical characteristics of normoalbuminuric (NA) and microalbuminuric (MA) type 2 diabetic patients.
Characteristics
NA 1a
MA 1a
NA 2b
MA 2b
NA 3c
MA 3c
NA 4d
MA 4d
()
()
()
()
()
()
()
()
Gender (M/F)
4/5
5/4
5/4
4/5
5/4
4/5
9/7
9/7
Mean age (years)
(49–72)
(55–82)
(54–67)
(56–65)
(56–73)
(41–72)
(49–72)
(44–82)
Duration of diabetes (years)
BMI (kg/m2)
Fasting plasma glucose (mg/dL)
HbA1C (%)
Blood urea nitrogen (mg/dL)
Serum creatinine (mg/dL)
Serum total cholesterol (mg/dL)
Serum HDL cholesterol (mg/dL)
Serum LDL cholesterol (mg/dL)
Serum triglycerides (mg/dL)
177 ± 134.7
Albumin : creatinine ratio (mg/g)
120.5 ± 70.7e
82.6 ± 41.9f
g
h
Pooled urine concentration (mg/mL)
a–cSample sets for the three iTRAQ experiments, dsample sets for 2-DE, e for NA1 versus MA1, f for NA2 versus MA2, g for NA3 versus MA3, and h for NA4 versus MA4. Data are expressed as the mean ± SD.