Simple Cystatin C Formula for Estimation of Glomerular Filtration Rate in Overweight Patients with Diabetes Mellitus Type 2 and Chronic Kidney Disease

Table 1

Diagnostic accuracy (area under the ROC curves, sensitivity, specificity) and comparison of ROC curves at cut-off value for GFR 60 mL/min/1.73 m² of calculated clearance from the C&G formula, the MDRD formula, the CKD-EPI formula, the CKD-EPI creatinine and cystatin formula, and the simple cystatin C formula. The GFR determined with ⁵¹CrEDTA was used as the gold standard.

Equation	AUC	Sensitivity; %	Specificity; %	𝑃^∗ value
C&G formula	0.915	93.0	81.5	0.162
MDRD formula	0.961	96.3	83.7	0.866
CKD-EPI formula	0.962	83.7	96.3	0.891
CKD-EPI creatinine and cystatin formula	0.982	92.6	96.5	0.322
Simple cystatin C formula	0.966	84.9	100

𝑃^∗ calculated according to the simple cystatin C formula.
AUC: area under the curve.