Propyl Gallate Plays a Nephroprotective Role in Early Stage of Diabetic Nephropathy Associated with Suppression of Glomerular Endothelial Cell Proliferation and Angiogenesis

Figure 3

Double immunofluorescent staining of CD31 (green, an endothelial cell marker) and PCX (red, a podocyte marker). ((a) and (b)) Control group, (c) ((a) and (b)) Merged. ((d) and (e)) Diabetic nephropathy group, (f) ((d) and (e)) Merged. ((g) and (h)) Diabetic nephropathy treated with propyl gallate group, (i) ((g) and (h)) Merged. Enhanced CD31 staining was observed in diabetic rat glomeruli. The PCX staining was mostly adjacent to CD31 staining, but there were some CD31 staining areas lacked adjacent PCX staining (arrow and arrowhead) in diabetic nephropathy model group.

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