Research Article

Propyl Gallate Plays a Nephroprotective Role in Early Stage of Diabetic Nephropathy Associated with Suppression of Glomerular Endothelial Cell Proliferation and Angiogenesis

Table 2

Oxidative stress parameters in different groups (means ± SD). Data show increased oxidative stress in DN glomeruli, and propyl gallate treatment improve the intra-glomerular oxidative state.

groupMDA (nmol/mgpro)Cu Zn—SOD (NU/mgpro)CAT (U/mgpro)GSH—Px (U/mgpro)

Control group 3 . 5 7 ± 0 . 1 4 1 4 . 3 8 ± 3 . 5 7 7 . 4 3 ± 1 . 9 5 1 1 . 3 5 ± 3 . 3 7
DN group 9 . 4 8 ± 1 . 3 3 * 7 . 8 4 ± 2 . 5 8 * 3 . 7 4 ± 0 . 5 7 * 7 . 7 3 ± 1 . 6 3 *
PG group 6 . 3 8 ± 1 . 8 1 # 1 0 . 1 5 ± 1 . 4 1 # 5 . 3 3 ± 0 . 8 2 # 1 0 . 5 1 ± 2 . 7 3 #

*Significantly different compared to control group ( 𝑃 < 0 . 0 5 ). #Significantly different compared to DN group ( 𝑃 < 0 . 0 5 ).