Renal Podocyte Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

Figure 1

Renal histopathology and function(a). Periodic acid-Schiff staining of glomeruli, ×400 magnification (b). Masson’s trichrome stained renal sections, ×400 magnification (c). Albuminuria in normal rat (NOR), spontaneously diabetic Torii rat (SDT) and SDT rat treated with 350 mg/kg metformin (MET). All data are expressed as mean ± SE (𝑛=8). ^∗𝑃<0.01 versus NOR group, ^#𝑃<0.01 versus SDT group.

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