Table of Contents Author Guidelines Submit a Manuscript
Experimental Diabetes Research
Volume 2012, Article ID 231502, 9 pages
http://dx.doi.org/10.1155/2012/231502
Clinical Study

Low Levels of Serum Paraoxonase Activities are Characteristic of Metabolic Syndrome and May Influence the Metabolic-Syndrome-Related Risk of Coronary Artery Disease

1Department of Medicine, University of Verona, Policlinico G.B. Rossi, 37134 Verona, Italy
2Department of Life and Reproduction Sciences, University of Verona, 37134 Verona, Italy

Received 30 June 2011; Accepted 20 July 2011

Academic Editor: Jun Ren

Copyright © 2012 Nicola Martinelli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [22 citations]

The following is the list of published articles that have cited the current article.

  • Qun Lu, Gang Tian, Yong Zhang, Min Lu, and Ai-Qun Ma, “Association between paraoxonase concentration and risk of acute coronary syndrome,” Chinese Journal of Cardiology, vol. 40, no. 7, pp. 579–582, 2012. View at PublisherView at Google Scholar
  • Ahmet Koc, Murad Cengiz, Zeynep Canan Ozdemir, and Hakim Celik, “ Paraoxonase and Arylesterase Activities in Children With Iron Deficiency Anemia and Vitamin B 12 Deficiency Anemia ,” Pediatric Hematology-Oncology, vol. 29, no. 4, pp. 345–353, 2012. View at PublisherView at Google Scholar
  • Natàlia Ferré, Albert Feliu, Anabel García-Heredia, Judit Marsillach, Neus París, Marta Zaragoza-Jordana, Bharti Mackness, Michael Mackness, Joaquín Escribano, Ricardo Closa-Monasterolo, Jorge Joven, and Jordi Camps, “Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome,” Clinical Biochemistry, 2013. View at PublisherView at Google Scholar
  • Nicola Martinelli, Anabel Garcia-Heredia, Helena Roca, Nuria Aranda, Victoria Arija, Bharti Mackness, Michael Mackness, Fabiana Busti, Gerard Aragones, Juan Pedro-Botet, Federica Pedica, Ivana Cataldo, Judit Marsillach, Jorge Joven, Domenico Girelli, and Jordi Camps, “Paraoxonase-1 status in patients with hereditary hemochromatosis,” Journal of Lipid Research, vol. 54, no. 5, pp. 1484–1492, 2013. View at PublisherView at Google Scholar
  • Guojun Zhang, Yimin Sun, Wenjin Li, Zhiqiang Li, Hong Lv, Yonghong Ren, Ruimin Ma, Xiaohong Li, Xixiong Kang, and Yongyong Shi, “Association between paraoxonase gene and stroke in the Han Chinese population,” BMC Medical Genetics, vol. 14, no. 1, 2013. View at PublisherView at Google Scholar
  • Fa Abessolo, Mj Bruno, Ma N'negue, M Yangou, and E Ngou-Milama, “Enzymatic and genetic polymorphisms of paraoxonase-1 in the Gabonese population: the relation to lipid parameters in patients with diabetes,” Journal of Endocrinology, Metabolism and Diabetes of South Africa, vol. 17, no. 2, pp. 92–99, 2014. View at PublisherView at Google Scholar
  • Giuseppe Penno, Laura Pucci, Daniela Lucchesi, Roberto Pedrinelli, Giulia Dell'Omo, and Stefano Del Prato, “Q192R paraoxonase (PON)1 polymorphism, insulin sensitivity, and endothelial function in essential hypertensive men,” Clinical Medicine Insights: Cardiology, vol. 8, pp. 57–62, 2014. View at PublisherView at Google Scholar
  • S. Civelek, M. Kutnu, H. Uzun, F. Erdenen, E. Altunoglu, G. Andican, A. Seven, A. O. Sahin, and G. Burcak, “Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic Syndrome,” Journal of Clinical Laboratory Analysis, 2014. View at PublisherView at Google Scholar
  • Chiara Cristina Bortolasci, Heber Odebrecht Vargas, Andre Souza-Nogueira, Estefania Gastaldello Moreira, Sandra Odebrecht Vargas Nunes, Michael Berk, Seetal Dodd, Decio Sabbatini Barbosa, and Michael Maes, “Paraoxonase (PON)1 Q192R functional genotypes and PON1 Q192R genotype by smoking interactions are risk factors for the metabolic syndrome, but not overweight or obesity,” Redox Report, vol. 19, no. 6, pp. 232–241, 2014. View at PublisherView at Google Scholar
  • Chiara Cristina Bortolasci, Heber Odebrecht Vargas, André Souza-Nogueira, Estefania Gastaldello Moreira, Sandra Odebrecht Vargas Nunes, Michael Berk, Seetal Dodd, Décio Sabbatini Barbosa, and Michael Maes, “Paraoxonase (PON)1 Q192R functional genotypes and PON1 Q192R genotype by smoking interactions are risk factors for the metabolic syndrome, but not overweight or obesity,” Redox Report, vol. 19, no. 6, pp. 232–241, 2014. View at PublisherView at Google Scholar
  • Thalia M.T. Avelar, Amanda S. Storch, Luana A. Castro, Gabriela V.M.M. Azevedo, Leda Ferraz, and Patricia F. Lopes, “Oxidative stress in the pathophysiology of metabolic syndrome: Which mechanisms are involved?,” Jornal Brasileiro de Patologia e Medicina Laboratorial, vol. 51, no. 4, pp. 231–239, 2015. View at PublisherView at Google Scholar
  • Monica Gomaraschi, Alice Ossoli, Maria Pia Adorni, Elisabetta Damonte, Eric Niesor, Fabrizio Veglia, Guido Franceschini, Renee Benghozi, and Laura Calabresi, “Fenofibrate and extended-release niacin improve the endothelial protective effects of HDL in patients with metabolic syndrome,” Vascular Pharmacology, 2015. View at PublisherView at Google Scholar
  • Hatem Ari, Mehmet Kayrak, Mehmet Gündüz, Fatih Kayhan, Zeynettin Kaya, Aysel Kiyici, and Faruk Uguz, “Association of paraoxonase-1 activity and major depressive disorder in patients with metabolic syndrome,” International Journal of Diabetes in Developing Countries, 2015. View at PublisherView at Google Scholar
  • Kannadasan AnandBabu, S.R. Bharathidevi, Sarangapani Sripriya, Parveen Sen, Vadivelu Jaya Prakash, Appukuttan Bindu, Natarajan Viswanathan, and Narayanasamy Angayarkanni, “Serum Paraoxonase activity in relation to lipid profile in Age-related Macular Degeneration patients,” Experimental Eye Research, 2016. View at PublisherView at Google Scholar
  • Mohit Rojekar, Mukund Mogarekar, and Arati Adhe-Rojekar, “Study of oxidative stress marker serum paraoxonase in metabolic syndrome,” Turkish Journal of Endocrinology and Metabolism, vol. 20, no. 3, pp. 83–87, 2016. View at PublisherView at Google Scholar
  • Krithika Srikanthan, Andrew Feyh, Haresh Visweshwar, Joseph I. Shapiro, and Komal Sodhi, “Systematic Review of Metabolic Syndrome Biomarkers: A Panel for Early Detection, Management, and Risk Stratification in the West Virginian Population,” International Journal Of Medical Sciences, vol. 13, no. 1, pp. 25–38, 2016. View at PublisherView at Google Scholar
  • Anna Aiello, Danilo Di Bona, Giuseppina Candore, Ciriuaco Carru, Angelo Zinellu, Giuseppe Di Miceli, Aldo Nicosia, Caterina Maria Gambino, Paolo Ruisi, calogero caruso, Sonya Vasto, and Giulia Accardi, “Targeting ageing with functional food: pasta with Opuntia single arm pilot study,” Rejuvenation Research, 2017. View at PublisherView at Google Scholar
  • Susana Meijide, Irantzu P?rez-Ruiz, M. Luisa Hern?ndez, Rosaura Navarro, Marcos Ferrando, Zaloa Larreategui, Jos?-Ignacio Ruiz-Sanz, and M Bego?a Ruiz-Larrea, “Paraoxonase activities in human follicular fluid: role in follicular maturation,” Reproductive BioMedicine Online, 2017. View at PublisherView at Google Scholar
  • Violet Kasabri, Randa Naffa, Qutaiba Qusay Al-Heety, Amal Akour, and Samar Abu Rkhaya, “Cross-sectional correlates of paraoxonase 1 and soluble intercellular adhesion molecule-1 in metabolic syndrome patients with and without diabetes,” Therapeutic Advances in Endocrinology and Metabolism, vol. 9, no. 10, pp. 303–310, 2018. View at PublisherView at Google Scholar
  • Behdokht Fathi Dizaji, Mahdi Rivandi, Ali Javandoost, Maryam Saberi Karimian, Atena Raei, Amirhossein Sahebkar, Gordon Ferns, Majid Ghayour Mobarhan, and Alireza Pasdar, “Association of genetic polymorphisms of PON1 and CETP with the presence of metabolic syndrome; the effects of genotypes on their serum activity and concentrations,” Egyptian Journal of Medical Human Genetics, 2018. View at PublisherView at Google Scholar
  • Riger, Gmoshniskiy, Khanferyan, Evstratova, and Apryatin, “Importance of the Leptin/Grelin ratio as a biomarker in dietary induced hyperlipidemia in female C57Black/6 Mice,” Medical Immunology (Russia), vol. 20, no. 3, pp. 341–352, 2018. View at PublisherView at Google Scholar
  • Mogarekar, Arati Adhe-Rojekar, Mukund Ramchandra, and Mohit Vijay Rojekar, “Paraoxonase activity in metabolic syndrome in children and adolescents,” Caspian Journal of Internal Medicine, vol. 9, no. 2, pp. 116–120, 2018. View at PublisherView at Google Scholar