Low Levels of Serum Paraoxonase Activities are Characteristic of Metabolic Syndrome and May Influence the Metabolic-Syndrome-Related Risk of Coronary Artery Disease

Table 2

Serum paraoxonase (PON1) activities, HDL cholesterol, and apolipoprotein A-I (Apo A-I) concentrations and LDL cholesterol/Apo B ratio according to the number of metabolic syndrome (MS) abnormalities.

	0 MS element (𝑛=35)	1 MS element (𝑛=78)	2 MS elements (𝑛=92)	3 MS elements (𝑛=50)	4 MS elements (𝑛=31)	5 MS elements (𝑛=7)	P *
TBBLase activity (U/mL)	3.60±1.38	3.46±0.95	3.38±0.80	3.08±0.99	2.98±1.13	2.69±0.56	<0.001*
DEPCyMCase activity (mU/mL)	24.49±7.62	23.97±5.90	23.45±4.49	21.74±5.96	19.36±6.23	17.92±4.37	<0.001
Paraoxonase activity (U/L)	128.4±103.7	118.8±69.2	119.5±77.1	102.2±63.0	103.6±89.7	101.4±38.3	NS
Arylesterase activity (kU/L)	106.3±35.7	101.3±31.1	99.3±30.0	89.1±34.0	85.6±32.3	76.0±21.0	<0.001
Normalized Lactonase Activity	145.4±23.3	145.3±24.4	144.7±24.9	140.8±31.9	152.8±39.1	154.3±34.7	NS
HDL cholesterol (mmol/L)	1.25±0.26	1.19±0.25	1.14±0.25	1.05±0.23	0.97±0.15	0.83±0.19	<0.001
Apo A-I(g/L)	1.38±0.25	1.31±0.27	1.27±0.26	1.18±0.25	1.09±0.17	0.93±0.21	<0.001
LDL cholesterol-to-Apo B ratio (mmol/g)	3.32±0.43	3.31±0.73	3.21±0.65	3.04±0.65	2.97±0.45	2.88±0.57	0.001

*by ANOVA with polynomial contrast for linear trend.