Amelioration of Glucose Control Mobilizes Circulating Pericyte Progenitor Cells in Type 2 Diabetic Patients with Microangiopathy

Figure 2

Effects of glucose control on HbA1c and PPCs. (a) There were no differences in HbA1c levels in patients with and without microangiopathy during time (*𝑃<0.05 versus baseline). (b) Increase in PPC levels was seen only in patients with microangiopathy (ANOVA 𝑃<0.05; *post hoc 𝑃<0.05). (c–f) Patients were divided according to the presence of micro-/macroalbuminuria, neuropathy, retinopathy, and peripheral arterial disease (PAD): a significant PPCs increase was detected in patients with urinary albumin-creatinine ratio (ACR) >30 mg/g and in the presence of neuropathy (ANOVA 𝑃<0.05; *post hoc 𝑃<0.05).

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