Adipocytokine Levels in Genetically High Risk for Type 2 Diabetes in the Indian Population: A Cross-Sectional Study
Table 1
Showing baseline anthropometric and biochemical characteristics of three study groups.
Parameters
Non-diabetic ()
Single parent diabetic ()
Both parents diabetic ()
value
BMI (kg/m2)
21.8 ± 3.3
22.4 ± 4.1
23.6 ± 3.5
0.042*
WHR
0.81 (0.79–0.83)
0.82 (0.80–86)
0.82 (0.83–88)
0.184#
BP—systolic (mmHg)
110.46 ± 5.9
110.29 ± 6.7
110.49 ± 4.9
0.996#
BP—diastolic (mmHg)
75.40 ± 3.9
74.43 ± 3.7
75.68 ± 4.1
0.083#
Fasting serum insulin ( IU/mL)
8.06 ± 0.99
10.79 ± 1.5
11.12 ± 1.3
<0.001**
Fasting serum glucose (mg/dL)
73.4 ± 8.5
78.02 ± 10.1
82.4 ± 9.7
<0.001**
2 h glucose of OGTT (mg/dL)
115.0 ± 6.4
116.9 ± 5.5
117.0 ± 5.9
0.060#
HbA1c (%)
4.3 ± 0.55
4.5 ± 0.49
4.53 ± 0.510
0.298#
HOMA-IR
1.45 ± 0.23
2.09 ± 0.49
2.26 ± 0.41
<0.001**
TNF- (pg/mL)
15.24 ± 3.5
16.06 ± 5.1
17.55 ± 5.8
0.038*
IL-6 (pg/mL)
112.3 ± 19.4
114.3 ± 19.9
119.0 ± 18.8
0.176#
Leptin (ng/mL)
12.3 3.3
12.7 ± 1.8
13.1 ± 1.7
0.199#
Adiponectin (g/mL)
11.0 1.2
9.5 ± 1.3
8.7 ± 1.0
<0.001**
Results are presented as mean SD or median (interquartile range, 25–75%). **; *; #; BMI: body mass index; WHR: waist to hip ratio; BP: blood pressure; OGTT: oral glucose tolerance test; HbA1c: glycated hemoglobin; HOMA-IR: homeostasis model assessment-insulin resistance; TNF-: tumor necrotic factor-alpha; IL-6: interleukin-6.
