Research Article

Hepatic Mitochondrial Alterations and Increased Oxidative Stress in Nutritional Diabetes-Prone Psammomys obesus Model

Figure 2

Mitochondrial respiration in Psammomys. Oxygen consumption rates (JO2) were assayed on mitochondria freshly isolated from control (open bars) or treated Psammomys (black bars), in the presence of glutamate/malate (a) or succinate/malate with rotenone (b) as energizing substrates. Various respiratory states were next assessed following the addition of different drugs. *P < 0.05 versus control group.
430176.fig.002a
(a)
430176.fig.002b
(b)