The Biological Behaviors of Rat Dermal Fibroblasts Can Be Inhibited by High Levels of MMP9
Figure 1
Establishment of the fibroblasts cell model of high matrix metalloproteinase 9 (MMP9) expression. The expressions of MMP9 mRNA, protein levels, and protease activity in model group were 6.05-, 4.12-, and 1.62-fold, respectively, greater than those in control group, which suggested that high expression of MMP9 was induced. When the cells were treated with tissue inhibitor of metalloproteinase 1 (TIMP1), the expression of MMP9 mRNA and protein had no statistical differences compared with model group. * versus control group. Data are mean ± SEM, .
