Influence of Tumour Necrosis Factor Alpha on the Outcome of Ischaemic Postconditioning in the Presence of Obesity and Diabetes

Figure 5

Effects of diabetes on physiological parameters in TNF-WT mice. Body weight was decreased 5 days post STZ treatment and returned to normal at day 10 post STZ treatment (a). Heart weight was reduced 10 days post STZ treatment (b). Insulin and leptin levels were both decreased with post STZ treatment (d and e) while STZ increased baseline blood glucose at days 5 and 10, *𝑃<0.05 and ***𝑃<0.001 versus no STZ.

(a)

(b)

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(e)