Antioxidant Sol-Gel Improves Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats
Figure 7
Immunohistochemical evidence of keratinization by loricrin at 14th day. Wounds treated with saline control (a), Pluronic F127 sol (b), saline plus vitamin C (c), and Pluronic F127 plus vitamin C (d) were demonstrated. Original magnifications taken at ×100 and ×200 as inset. Immunohistochemical staining by antiloricrin (epidermal differentiation marker) antibodies showed that loricrin was highly expressed in the upper granular cell layer, especially in the regenerated epidermis of Pluronic F127 plus vitamin C or saline plus vitamin C groups.
