Circulating TGF-β1, Glycation, and Oxidation in Children with Diabetes Mellitus Type 1

Table 1

Clinical and biochemical parameters in all diabetic patients and healthy control.

Parameter	All patients withDM1	𝑛	Controls	𝑁
Age (r.)	15.2±2.7	79	9.2±4.9	31
Duration of DM (r.)	8.7±3.0	79	—	—
UAER (𝜇g/min)	37.8±116.8	74	—	—
FAM (mmol/L)	2.85±0.50	75	1.62±0.35^#	29
HbA1c (%)	9.51±1.90	79	5.0±0.39^#	21
s-AGEs (A.U.)*	67.85 (61.6; 76.4)	70	58.2 (52.0; 65.5)^#	29
AOPP (𝜇mol/L)*	80.5 (44.9; 139.9)	59	58.5 (51.5; 66.9)^#	12
LPO(nmol/mL)*	119 (100.3; 156.3)	48	99 (67; 106)^#	11
TGF-𝛽 (ng/mL)*	7.1 (3.6; 12.6)	29	1.6 (0.8; 3.9)^#	9

The results are presented as mean ± SD in normal distribution and as median (1st quartile, 3rd quartile) in data with abnormal distribution.* 
^#significant difference in comparison with DM1 patients.