Genetic Dissection of Complex Genetic Factor Involved in NIDDM of OLETF Rat

Table 1

NIDDM loci and their actions to increase glucose levels in combination with body weight.

Locus	Mapping method	Chromosome	Trait	LOD score	Action of gene
Nidd1/of	Interval	7	Glucose 60 min	4.33	Interaction
Nidd2/of	Interval	14	Glucose AUC	5.15	Interaction
Nidd3/of	Interval	8	Glucose 30 min	3.06	Direct action
Nidd4/of	Interval	11	Fasting glucose	3.70	Direct action
Nidd5/of	Interval	1	Fasting glucose	2.82	Direct action
Nidd6/of	Interval	1	Glucose 30 min	3.79	Pleiotropic
Nidd7/of	Interval	5	Fasting glucose	3.54	Direct action
Nidd8/of	Interval	9	Glucose 90 min	3.87	Interaction
Nidd9/of	Interval	12	Fasting glucose	3.72	Interaction
Nidd10/of	Interval	14	Glucose 60 min	4.06	Interaction
Nidd11/of	Interval	16	Glucose 60 min	3.54	Pleiotropic
Nidd12/of	MQM	5	Glucose AUC	3.98	Interaction
Nidd13/of	MQM	7	Fasting glucose	3.90	Direct action
Nidd14/of	MQM	17	Glucose AUC	4.20	Direct action