Oxidative/Nitrosative Stress and Protein Damages in Aqueous Humor of Hyperglycemic Rabbits: Effects of Two Oral Antidiabetics, Pioglitazone and Repaglinide

Table 2

Blood glucose and plasma insulin concentrations in control and hyperglycemic rabbits at the start and the end of experiment.

Group	Glucose (mmol/L)		Insulin (mU/L)
	Start	End	Start	End
Control (C)	6.2±0.1	5.7±0.3	13.16±1.26	13.30±1.12
Control-pioglitazone (CP)	6.5±0.3	5.9 ± 0.3^b	11.74±0.72	14.12 ± 0.98^b
Control-repaglinide (CR)	6.3±0.2	4.0 ± 0.3^a,b,*	12.83±1.01	20.0 ± 1.42^a,b,*
Hyperglycemic (H)	26.3 ± 2.3^a	24.9 ± 2.8^a	3.21 ± 0.63^a	2.79 ± 0.79^a
Hyperglycemic-pioglitazone (HP)	27.2 ± 0.3^a	23.9 ± 1.8^a	2.31±0.15	2.01 ± 0.34^a
Hyperglycemic-repaglinide (HR)	26.4 ± 1.2^a	24.0 ± 2.3^a	2.32 ± 0.15^a	2.02 ± 0.04^a

Values are mean ± SEM (𝑛=5). ^aSignificant at 𝑃<0.05 versus Group C. ^bSignificant at 𝑃<0.05 versus Group H. *Significant at 𝑃<0.05 versus start.