Research Article
Angiotensin-Converting Enzyme Genotype and Peripheral Arterial Disease in Diabetic Patients
Table 1
Comparisons of characteristics of study subjects with and without peripheral arterial disease.
| | Characteristics | Peripheral arterial disease | | | Yes | No |
| | 81 | 864 | | | Age, years | 72.9 (7.3) | 62.6 (11.3) | <0.001 | | Sex | | | | | Men | 31 (38.3) | 423 (49.0) | 0.066 | | Women | 50 (61.7) | 441 (51.0) | | | Duration of diabetes, years | 16.3 (9.3) | 10.8 (7.7) | <0.001 | | Body mass index, kg/m2 | 23.6 (3.3) | 24.9 (3.4) | 0.001 | | Smoking | | | | | Never smokers | 51 (63.0) | 560 (64.9) | >0.1 | | Current or former smokers | 30 (37.0) | 303 (35.1) | | | Hypertension | | | | | No | 17 (21.0) | 369 (42.7) | <0.001 | | Yes | 64 (79.0) | 495 (57.3) | | | Systolic blood pressure, mmHg | 146.0 (18.2) | 134.0 (17.3) | <0.001 | | Diastolic blood pressure, mmHg | 82.9 (12.0) | 83.4 (9.6) | >0.1 | | Hemoglobin , % | 7.9 (1.6) | 7.9 (1.9) | >0.1 | | Dyslipidemia | | | | | No | 18 (22.2) | 316 (36.6) | 0.010 | | Yes | 63 (77.8) | 548 (63.4) | | | Total cholesterol, mg/dL | 209.7 (42.2) | 205.1 (43.3) | >0.1 | | Ln(triglycerides), mg/dL | 5.1 (0.6) | 5.0 (0.6) | 0.03 | | High-density lipoprotein cholesterol, mg/dL | 46.8 (12.7) | 48.1 (13.6) | >0.1 | | Low-density lipoprotein cholesterol, mg/dL | 115.5 (34.9) | 114.2 (33.8) | >0.1 | | Ln[lipoprotein (a)], mg/dL | 5.0 (1.2) | 4.7 (1.1) | 0.011 | | Uric acid, mg/dL | 5.9 (2.2) | 5.2 (2.0) | 0.006 | | Angiotensin-converting enzyme genotype | | | | | II | 35 (43.2) | 430 (49.8) | >0.1 | | ID | 34 (42.0) | 358 (41.4) | | | DD | 12 (14.8) | 76 (8.8) | | | Allele frequency | | | | | I | 104 (64.2) | 1,218 (70.5) | >0.1 | | D | 58 (35.8) | 510 (29.5) | |
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Data are expressed as mean (SD) or (percentage).
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