Journal of Diabetes Research / 2012 / Article / Tab 3

Research Article

Angiotensin-Converting Enzyme Genotype and Peripheral Arterial Disease in Diabetic Patients

Table 3

Gene transmission models for insertion/deletion (I/D) polymorphism of angiotensin-converting enzyme gene on peripheral arterial disease.

Gene transmissionchi-square testLogistic regression*
Total Peripheral arterial
disease, (%)
valueAdjusted odds ratio
(95% confidence interval)
valueAkaike
information
criterion
NoYes

Recessive model
 II/ID857788 (91.9) 69 (8.1)1.00
 DD8876 (86.4)12 (13.6)0.0752.48 (1.18–5.21)0.017425.880
Dominant model
  II465430 (92.5)35 (7.5)1.00
 ID/DD480434 (90.4)46 (9.6)0.2591.69 (1.00–2.85)0.050427.157
Additive model
 II = 0,465430 (92.5)35 (7.5)1.00
 ID = 1,392358 (91.3)34 (8.7) 1.64 (1.12–2.39) per risk
 DD = 28876 (86.4)12 (13.6)0.171allele0.010424.612

*Adjusted variables include age, sex, body mass index, duration of diabetes, hemoglobin , uric acid, ln[lipoprotein (a)], hypertension, smoking, and dyslipidemia.

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