Effect of Exercise on Kidney Function, Oxidative Stress, and Inflammation in Type 2 Diabetic KK-A^y Mice

Figure 3

Number of MCP-1 positive cells and staining in each mouse at 20 weeks of age. The number of MCP-1 positive cells in sedentary KK-𝐴^𝑦 mice was significantly greater compared with that in the exercised KK-𝐴^𝑦 mice and also sedentary KK mice. Representative MCP-1 staining in the renal cortex of sedentary KK (b), sedentary KK-𝐴^𝑦 (c), low-intensity exercised KK-𝐴^𝑦 (d), and moderate-intensity exercised KK-𝐴^𝑦 mice. (e) Staining (a) depicts the absence of primary antibody. Images were taken at 100-fold magnification. ^∗𝑃<0.05^†𝑃<0.001.