Journal of Diabetes Research / 2012 / Article / Tab 4

Clinical Study

The Common C49620T Polymorphism in the Sulfonylurea Receptor Gene SUR1 (ABCC8) in Patients with Gestational Diabetes and Subsequent Glucose Metabolism Abnormalities

Table 4

Relationships between the polymorphism C49620T in the SUR1 (ABCC8) gene and glucose metabolism parameters, -cell function, and insulin resistance in the GDM (+) group.

ParameterCC
Mean ± SD (n = 54)
CT
Mean ± SD (n = 96)
TT
Mean ± SD (n = 49)
P value
CC versus CT
P value
CT versus TT
P value
CC versus TT

Glucose 0 (mmol/L)5.3 ± 0.85.3 ± 0.75.4 ± 0.7NSNSNS
Glucose 60 (mmol/L)7.9 ± 2.38.5 ± 2.78.4 ± 2.50.0121NSNS
Glucose 120 (mmol/L)6.2 ± 2.16.6 ± 2.36.2 ± 2.1NSNSNS
Insulin 0 ( IU/mL)12.5 ± 6.113.6 ± 8.515.0 ± 11.2NSNSNS
Insulin 60 ( IU/mL)96.7 ± 43.9109.9 ± 64.1112.0 ± 76.4NSNSNS
Insulin 120 ( IU/mL)64.3 ± 48.678.4 ± 54.478.5 ± 75.40.0483NSNS
HbA1c (%)5.6 ± 0.55.7 ± 0.45.7 ± 0.4NSNSNS
HOMA IR1.63 ± 0.801.77 ± 1.081.91 ± 1.22NSNSNS
HOMA %B121.9 ± 48.0126.3 ± 51.9126.8 ± 60.1NSNSNS
HOMA %S77.4 ± 46.371.2 ± 31.669.1 ± 41.8NSNSNS

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