Research Article

Impact of Diabetes and Hyperglycemia on Survival in Advanced Breast Cancer Patients

Table 1

Clinical and pathological characteristics in nondiabetic and diabetic patients.

NondiabeticsDiabeticsUnivariate (P)

Median age (Years)48.052.50.207
T
 127 (12%) 4 (9%) 0.684
 277 (34%) 12 (29%)
 354 (24%) 14 (35%)
 467 (30%)10 (27%)

N
 041 (18%) 9 (23%) 0.695
 195 (42%) 14 (34%)
 256 (25%) 8 (20%)
 333 (15%)9 (23%)

Grade
 129 (13%) 7 (18%) 0.087
 281 (36%) 20 (49%)
 3115 (51%)13 (33%)

Hormone receptor
 Positive112 (49%) 28 (70%) 0.018
 Negative113 (51%)12 (30%)

HER2
 Positive 60 (27%) 5 (13%) 0.079
 Negative165 (73%)35 (87%)

Triple-negative
 Positive 59 (26%) 7 (18%) 0.262
 Negative166 (74%)33 (82%)

Metastatic site
 Single 122 (54%) 18 (45%) 0.306
 Multiple103 (46%)22 (55%)

Type of metastases
 Nonvisceral 86 (38%) 16 (40%) 0.790
 Visceral139 (62%)24 (60%)

Median BMI at recurrence26.827.50.359

T: tumor stage according to TNM; N: nodal stage according to TNM; BMI: body mass index.