Serum CA19-9 Level Associated with Metabolic Control and Pancreatic Beta Cell Function in Diabetic Patients

Table 2

Basic clinical and biochemical characteristics by quartiles of CA19-9.

Variables	CA19-9 quartile				𝑃 value
	1 (Lowest)	2	3	4 (Highest)
Age (y)	56.64±12.198	60.1±12.652^*	58.75±13.534	58.21±13.806	0.023
Duration (y)	8.0 (3.0–12.0)	9.0 (4.0–12.5)	8.0 (3.0–13.0)	8.0 (3.0–13.0)	0.327
ALT (U/L)	17.00 (13.00–26.00)	19.00 (13.75–30.00)	17.00 (13.00–75.00)	19.00 (12.00–29.00)	0.398
AST (U/L)	19.00 (15.00–24.00)	19.00 (16.00–24.75)	18.50 (16.00–24.00)	19.00 (16.00–25.00)	0.508
TC (mmol/L)	4.66±0.935	4.62±1.054	4.75±1.201	4.99±1.367^**##▲	0.001
TG (mmol/L)	1.45 (0.99–2.08)	1.43 (1.04–2.04)	1.47 (0.93–2.07)	1.44 (0.97–2.21)	0.739
HDL (mmol/L)	1.18±0.428	1.12±0.326^*	1.15±0.328	1.18±0.368	0.167
LDL (mmol/L)	3.11±0.849	3.10±0.914	3.16±1.032	3.27±1.086	0.168
BUN (mmol/L)	5.37±1.615	5.84±2.517	5.75±2.340	5.91±2.931	0.056
Cr (μmol/L)	67.00 (57.00–78.25)	68.00 (57.00–81.00)	64.00 (54.00–77.00)	63.00 (51.75–80.50)	0.363
FPG (mmol/L)	6.84±2.367	7.93±2.752^**	8.73±3.263^**#	9.15±4.116^**##	<0.001
2hPG (mmol/L)	10.77±4.70	13.72±4.812^**	13.95±5.285^**	14.72±5.471^**	<0.001
HbA1c (%)	7.36±1.870	8.41±1.945^**	9.43±2.444^**##	10.49±2.768^**##▲▲	<0.001
GA (%)	21.89±5.874	24.30±6.819^*	27.18±8.455^**##	30.29±9.525^**##▲▲	<0.001
CP0 (ng/mL)	2.195 (1.383–4.228)	1.80 (1.18–2.695)^*	1.705 (1.04–2.553)^**	1.29 (0.64–2.03)^**#	<0.001
CP120 (ng/mL)	5.32 (2.85–15.05)	4.21 (2.53–5.82)^**	3.27 (1.76–5.44)^**#	2.38 (1.31–4.15)^**#	<0.001
ΔCP (ng/mL)	2.76 (1.34–9.388)	2.09 (0.94–3.41)^**	1.55 (0.53–2.77)^**#	1.00 (0.41–2.06)^**#▲	<0.001

Data represent means ± S.D. or median (interquartile range), ^*𝑃<0.05, ^**𝑃<0.01 versus group 1; ^#𝑃<0.05,  ^##𝑃<0.01 versus proup 2; ^▲𝑃<0.05,  ^▲▲𝑃<0.01 versus proup 3.