Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Diet-Induced Metabolic Syndrome in Rats
Figure 9
Inflammation and fibrosis in the heart. Representative images of left ventricular interstitial collagen deposition stained in picrosirius red staining (×40) after 16 weeks in CS (a), HCHF (b), CS + t-AUCB (c), HCHF + t-AUCB (d). Wright’s staining of LV of the heart (×40) showing infiltration of inflammatory cells after 16 weeks in CS (e), HCHF (f), CS + t-AUCB (g), HCHF + t-AUCB (h). Wright’s staining of LV of the heart (×100) showing infiltration of mast cells after 16 weeks in HCHF (i), HCHF + t-AUCB (j). Summary data of left ventricular interstitial collagen deposition (k) after 16 weeks in CS, HCHF, CS + t-AUCB, HCHF + t-AUCB. * versus CS-fed rats, ** versus HCHF-fed rats.
