Pentoxifylline Attenuates Methionine- and Choline-Deficient-Diet-Induced Steatohepatitis by Suppressing TNF-α Expression and Endoplasmic Reticulum Stress
Figure 3
Hepatic histology and triglyceride content after 4 weeks of administration with an MCD diet and pentoxifylline. The liver sections were stained with H&E, Masson's trichrome, and oil-red O staining (). The liver of MCD-diet-fed rats showed yellowish markings. Rats administrated pentoxifylline showed the reduced yellow hepatic color and fat accumulation (a). Rats in groups III and IV have increased hepatic triglyceride content relative to rats in the control group. There was no statistical difference between groups III and IV (b). Results are shown as mean ± SEM. **P < 0.01 versus untreated control group.
