Genetic Variation in CYP17A1 Is Associated with Arterial Stiffness in Diabetic Subjects

Table 3

Frequencies of hypertension according to SNP genotypes.

			Prediabetes			Diabetes
	Genotype	Normotensive	Hypertensive	P (corrected P)	Normotensive	Hypertensive	P (corrected P)
rs5326	GG/GA/AA	162/101/15	19/16/2	0.6726	256/133/16	178/116/24	0.0265
(DRD1)	(%)	(58.3/36.3/5.4)	(51.4/43.2/5.4)	(1)	(63.2/32.8/4)	(56/36.5/7.5)	(1)
rs1004467	TT/TC/CC	122/124/32	16/18/4	0.9949	160/215/34	157/130/29	0.0020
(CYP17A1)	(%)	(43.9/44.6/11.5)	(42.1/47.4/10.5)	(1)	(39.1/52.6/8.3)	(49.7/41.1/9.2)	(0.1040)
rs2960306	GG/GT/TT	221/59/4	31/9/0	0.4793	336/73/6	234/79/8	0.0066
(GRK4)	(%)	(77.8/20.8/1.4)	(77.5/22.5/0)	(1)	(81/17.6/1.4)	(72.9/24.6/2.5)	(0.3432)
rs11191548	TT/TC/CC	151/110/22	25/11/2	0.3199	216/182/16	197/102/22	0.0078
(NT5C2)	(%)	(53.4/38.9/7.8)	(65.8/28.9/5.3)	(1)	(52.2/44/3.9)	(61.4/31.8/6.9)	(0.4056)
rs1530440	CC/CT/TT	194/78/7	18/19/3	0.0015	287/116/9	222/89/5	0.8878
(C10orf107)	(%)	(69.5/28/2.5)	(45/47.5/7.5)	(0.0780)	(69.7/28.2/2.2)	(70.3/28.2/1.6)	(1)