A Comparison of Inflammatory and Oxidative Stress Markers in Adipose Tissue from Weight-Matched Obese Male and Female Mice

Table 1

Characteristics of male and female C57BL/6 mice receiving a standard rodent chow or a high-fat diet (HFD).¹

	Male chow	Male HFD	Female chow	Female HFD
Body weight (g)	28.8±0.28^b	45.3±1.0^a	24.8±0.45^b	46.5±2.0^a
Age^2 (weeks)	21	21	38	38
Gonadal AT^3 (g)	0.51±0.28^c	2.25±0.17^b	0.44±0.05^c	3.74±0.35^a
Subcutaneous AT (g)	0.32±0.01^c	2.29±0.24^b	0.27±0.02^c	3.34±0.28^a
Blood glucose (mg/dL)	99±8^b	142±11^a	108±8^b	116±5^ab
Plasma estradiol (pg/mL)	—	—	92.5±1.53	92.7±0.35

¹Data are presented as means ± SE; means with different superscripts differ 𝑃<0.05; 𝑛=5–8.
²Age at which the HFD-fed group reached a body weight of 45 g and metabolic testing and tissue collection occurred.
³AT; adipose tissue.