Research Article
Associations of Common Variants at APLN and Hypertension in Chinese Subjects with and without Diabetes
Table 3
Analysis for the association of the three SNPs with hypertension in diabetic females.
| SNP | Genotype | NT | HT | OR (95% CI) | P | |
| rs2235307 | CC | 288 (63.6%) | 712 (68.8%) | 0.88 (0.54–1.42) | 0.143 | 0.592 | CT | 150 (33.1%) | 293 (28.3%) | TT | 15 (3.3%) | 30 (2.9%) |
| rs2235306 | TT | 150 (33.5%) | 318 (30.7%) | 1.19 (0.80–1.76) | 0.562 | 0.390 | TC | 217 (48.4%) | 525 (50.6%) | CC | 81 (18.1%) | 194 (18.7%) |
| rs3115759 | AA | 207 (45.3%) | 464 (44.2%) | 0.78 (0.53–1.15) | 0.485 | 0.212 | AG | 193 (42.2%) | 472 (45.0%) | GG | 57 (12.5%) | 113 (10.8%) |
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NT: normotensive subjects. HT: hypertensive subjects. P values were adjusted for age, body mass index, and diabetes duration.
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