Research Article

Associations of Common Variants at APLN and Hypertension in Chinese Subjects with and without Diabetes

Table 3

Analysis for the association of the three SNPs with hypertension in diabetic females.

SNPGenotypeNTHTOR (95% CI)P

rs2235307CC288 (63.6%)712 (68.8%)0.88 (0.54–1.42)0.1430.592
CT150 (33.1%)293 (28.3%)
TT15 (3.3%)30 (2.9%)

rs2235306TT150 (33.5%)318 (30.7%)1.19 (0.80–1.76)0.5620.390
TC217 (48.4%)525 (50.6%)
CC81 (18.1%)194 (18.7%)

rs3115759AA207 (45.3%)464 (44.2%)0.78 (0.53–1.15)0.4850.212
AG193 (42.2%)472 (45.0%)
GG57 (12.5%)113 (10.8%)

NT: normotensive subjects. HT: hypertensive subjects.
P values were adjusted for age, body mass index, and diabetes duration.