Journal of Diabetes Research / 2013 / Article / Fig 2

Research Article

Skeletal Muscle-Specific CPT1 Deficiency Elevates Lipotoxic Intermediates but Preserves Insulin Sensitivity

Figure 2

(a) Basal mitochondrial FAO was reduced in the skeletal muscle of knockout mice, compared with wild type (* ). (b) Ceramides were accumulated in skeletal muscles of knockout mice, especially for C16 and C18 (* ) but not for C18:1 or C24 or C24:1. (c) DAGs and TAGs were accumulated in skeletal muscles of knockout mice (* ). for each group.

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