Journal of Diabetes Research / 2013 / Article / Fig 5

Research Article

Effects of Long-Term Treatment with Ranirestat, a Potent Aldose Reductase Inhibitor, on Diabetic Cataract and Neuropathy in Spontaneously Diabetic Torii Rats

Figure 5

The total cataract scores at 40 weeks. The total cataract score of the untreated SDT rats at 40 weeks is significantly higher than that of the SD rats. , Wilcoxon rank sum test. The total cataract score of the SDT rats treated with ranirestat at 40 weeks is significantly lower than that of the untreated SDT rats. , Wilcoxon rank sum test. There is no significant difference in the total cataract score between the untreated SDT rats and the SDT rats treated with epalrestat. NDM: non-diabetes mellitus; DM: diabetes mellitus; rani: ranirestat; epa: epalrestat.
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