Association of the Receptor for Advanced Glycation End Products Gene Polymorphisms and Circulating RAGE Levels with Diabetic Retinopathy in the Chinese Population
Table 3
Multilocus genetic interaction model.
Model
Training balance accuracy
Testing balance accuracy
CVC
OR 95% CI
P value
G82S
0.5353
0.5238
9/10
1.3297 (1.03, 1.7163)
0.0286
2184A/G, G82S
0.5565
0.5232
6/10
1.5972 (1.2277, 2.078)
0.0005
2184A/G, G82S, −429T/C
0.5732
0.5187
4/10
2.1518 (1.5975, 2.8983)
<0.0001
2184A/G, 1704G/T, G82S, −429T/C
0.5957
0.5492
10/10
2.2254 (1.7115, 2.8935)
<0.0001
The best model has the maximum CVC and highest testing balance accuracy.