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Journal of Diabetes Research
Volume 2013 (2013), Article ID 421832, 10 pages
Review Article

Dietary Treatment Options for Depression among Diabetic Patient, Focusing on Macronutrients

1Food Security Research Center, Isfahan University of Medical Sciences, Isfahan 21871, Iran
2Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan 21871, Iran

Received 18 July 2013; Revised 28 August 2013; Accepted 29 August 2013

Academic Editor: Hiroshi Okamoto

Copyright © 2013 Fahimeh Haghighatdoost and Leila Azadbakht. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


There is a bidirectional adverse association between diabetes and depression. The odds for experiencing depressive symptoms in diabetic patients are two times more than nondiabetic persons, and depression is an independent predictor for the onset of diabetes. However, depression has been approximately unrecognized and untreated in two-thirds of diabetic patients, which may lead to worsened diabetes complications. A cornerstone strategy for managing depression among diabetic patients is the use of diet to improve both health problems. Because of similar pathophysiology for chronic diseases and depression, it seems that similar dietary recommendations could be useful. However, few studies have been conducted among diabetic patients. Regarding the complications of diabetes such as renal diseases and coronary heart diseases, the proper range of various macronutrients should be clarified in depressed diabetic patients as well as the proper type of each macronutrient. In this paper, we reviewed the available data on the treatment of depression in diabetic patients.