Both ERK/MAPK and TGF-Beta/Smad Signaling Pathways Play a Role in the Kidney Fibrosis of Diabetic Mice Accelerated by Blood Glucose Fluctuation

<table>BGF treatment enhanced ERK1/2 phosphorylation in the kidney of mice. The p38 activity was not sensitive to BGF treatment. Whole cell lysates were collected and subjected to Western blot analysis for phosphorylated ERK1/2, p38 and total ERK 1/2, p38.</table>

Journal of Diabetes Research

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Figure 4

Figure 4: Both ERK/MAPK and TGF-Beta/Smad Signaling Pathways Play a Role in the Kidney Fibrosis of Diabetic Mice Accelerated by Blood Glucose Fluctuation 

Figure 4 | Both ERK/MAPK and TGF-Beta/Smad Signaling Pathways Play a Role in the Kidney Fibrosis of Diabetic Mice Accelerated by Blood Glucose Fluctuation 